BDBM50142265 CHEMBL3759119
SMILES CC(C)C(=O)NCc1cc(C(=O)Nc2ncc[nH]2)c(Cl)cc1C
InChI Key InChIKey=LYZRMWQGYUWBNV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50142265
Affinity DataIC50: 8.85E+3nMAssay Description:Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta...More data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human microsomal PGES1 expressed in 293E cells by LC/MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of mPGES1 in LPS-induced human whole blood assessed as suppression of PGE2 response after 20 to 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair