BDBM50142332 CHEMBL9363::{[4-(2-Benzotriazol-1-yl-2-phenyl-ethyl)-phenyl]-difluoro-methyl}-phosphonic acid

SMILES OP(O)(=O)C(F)(F)c1ccc(CC(c2ccccc2)n2nnc3ccccc23)cc1

InChI Key InChIKey=ZCRYOGHINJUGNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142332   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142332({[4-(2-Benzotriazol-1-yl-2-phenyl-ethyl)-phenyl]-d...)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142332({[4-(2-Benzotriazol-1-yl-2-phenyl-ethyl)-phenyl]-d...)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) over-expressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142332({[4-(2-Benzotriazol-1-yl-2-phenyl-ethyl)-phenyl]-d...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed