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BDBM50142419 2-{(2R,5R)-2-(2,4-Dichloro-phenyl)-3-[2-(2-dimethylamino-acetylamino)-ethyl]-4-oxo-thiazolidin-5-yl}-N-naphthalen-1-ylmethyl-acetamide::CHEMBL290845

SMILES: CN(C)CC(=O)NCCN1[C@H](S[C@H](CC(=O)NCc2cccc3ccccc23)C1=O)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=BKRWVQBKJVTPBW-UFHPHHKVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142419   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 4 (CCR4)


(Homo sapiens (Human))
BDBM50142419
PNG
(2-{(2R,5R)-2-(2,4-Dichloro-phenyl)-3-[2-(2-dimethy...)
Show SMILES CN(C)CC(=O)NCCN1[C@H](S[C@H](CC(=O)NCc2cccc3ccccc23)C1=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H30Cl2N4O3S/c1-33(2)17-26(36)31-12-13-34-27(37)24(38-28(34)22-11-10-20(29)14-23(22)30)15-25(35)32-16-19-8-5-7-18-6-3-4-9-21(18)19/h3-11,14,24,28H,12-13,15-17H2,1-2H3,(H,31,36)(H,32,35)/t24-,28-/m1/s1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Array BioPharma

Curated by ChEMBL


Assay Description
Inhibition of [125I]-MDC binding to recombinant human C-C chemokine receptor type 4 (CCR4) expressed in murine pre-B cells


Bioorg Med Chem Lett 14: 1619-24 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.072
BindingDB Entry DOI: 10.7270/Q2W37VRK
More data for this
Ligand-Target Pair