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BDBM50142822 CHEMBL51982::N-tert-Butyl-4-[1'-(2-methyl-benzoyl)-[1,4']bipiperidinyl-4-ylmethyl]-benzamide

SMILES: Cc1ccccc1C(=O)N1CCC(CC1)N1CCC(Cc2ccc(cc2)C(=O)NC(C)(C)C)CC1

InChI Key: InChIKey=TWPFYIIQRRJSJP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142822   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50142822
PNG
(CHEMBL51982 | N-tert-Butyl-4-[1'-(2-methyl-benzoyl...)
Show SMILES Cc1ccccc1C(=O)N1CCC(CC1)N1CCC(Cc2ccc(cc2)C(=O)NC(C)(C)C)CC1
Show InChI InChI=1S/C30H41N3O2/c1-22-7-5-6-8-27(22)29(35)33-19-15-26(16-20-33)32-17-13-24(14-18-32)21-23-9-11-25(12-10-23)28(34)31-30(2,3)4/h5-12,24,26H,13-21H2,1-4H3,(H,31,34)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
106n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against cloned human muscarinic acetylcholine receptor M2.


Bioorg Med Chem Lett 14: 1791-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.033
BindingDB Entry DOI: 10.7270/Q22N51QH
More data for this
Ligand-Target Pair