BDBM50143282 (-)-cytisine::(1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::(1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::(1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one::(1R,9S)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::(1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one::1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one (cytisine)::CHEMBL497939::Cytisine1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one::cytisine

SMILES: C1[C@H]2CNC[C@@H]1C3=CC=CC(=O)N3C2

InChI Key: InChIKey=ANJTVLIZGCUXLD-UHFFFAOYSA-N

Data: 39 KI  1 IC50  10 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 50143282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit delta (Pacific electric ray)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		2.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Pacific electric ray)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		261	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50143282 ((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair