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BDBM50143496 4-(4-Dimethylaminomethyl-6-methoxy-1,2,3,4-tetrahydro-carbazole-9-sulfonyl)-phenylamine::CHEMBL175068

SMILES: COc1ccc2n(c3CCCC(CN(C)C)c3c2c1)S(=O)(=O)c1ccc(N)cc1

InChI Key: InChIKey=IXNYNYQNFGSYRR-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143496   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50143496
PNG
(4-(4-Dimethylaminomethyl-6-methoxy-1,2,3,4-tetrahy...)
Show SMILES COc1ccc2n(c3CCCC(CN(C)C)c3c2c1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1/C22H27N3O3S/c1-24(2)14-15-5-4-6-21-22(15)19-13-17(28-3)9-12-20(19)25(21)29(26,27)18-10-7-16(23)8-11-18/h7-13,15H,4-6,14,23H2,1-3H3
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PC sid
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Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cells


Bioorg Med Chem Lett 14: 1961-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.071
BindingDB Entry DOI: 10.7270/Q29887J8
More data for this
Ligand-Target Pair