BDBM50143558 CHEMBL41355::EZOGABINE::N-(2-amino-4-(4-fluorobenzylamino)-phenyl)carbamic acid ethylester::RETIGABINE::[2-Amino-4-(4-fluoro-benzylamino)-phenyl]-carbamic acid ethyl ester

SMILES: CCOC(=O)Nc1ccc(cc1N)NCc2ccc(cc2)F

InChI Key: InChIKey=PCOBBVZJEWWZFR-UHFFFAOYSA-N

Data: 23 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50143558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 4 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Mouse)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Mouse)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/member 3 (Rat)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Rat)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.21E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Mouse)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 5 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Rat)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 5 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 4 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<150	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2 (Human)	BDBM50143558 (CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair