BDBM50143607 (6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(RRR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::CHEMBL59092

SMILES C[C@H]1C2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143607   

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143607((RRR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.180nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143607((RRR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.320nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143607((RRR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed