BDBM50143828 3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl]-propionic acid::CHEMBL60090

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2sc(CCC(O)=O)cc12

InChI Key InChIKey=DZGIOQCOHRMFAU-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143828   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143828(3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi:  200nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143828(3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143828(3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration for Retinoic acid receptor alpha activity in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143828(3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  97nMAssay Description:Effective concentration for Retinoid X receptor alpha activity in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed