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BDBM50144707 3-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-propan-1-ol::CHEMBL75132

SMILES: CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CCCO)cc2)nc(N)n1

InChI Key: InChIKey=BUOALGQXEKDQOY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144707   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens (Human))
BDBM50144707
PNG
(3-{4-[2-Amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimid...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CCCO)cc2)nc(N)n1
Show InChI InChI=1S/C21H23ClN4O2/c1-2-28-19-10-7-15(22)12-17(19)18-13-20(26-21(23)25-18)24-16-8-5-14(6-9-16)4-3-11-27/h5-10,12-13,27H,2-4,11H2,1H3,(H3,23,24,25,26)
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PC sid
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Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Cell Therapeutics Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 2303-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.104
BindingDB Entry DOI: 10.7270/Q2Q23ZPH
More data for this
Ligand-Target Pair