BDBM50144799 CHEMBL3764795

SMILES: CC(Cc1ccc(cc1)C(=O)NCc1ccccc1C(F)(F)F)C(O)=O

InChI Key: InChIKey=DCCNWCBAKAPIQY-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50144799 (CHEMBL3764795) Show SMILES CC(Cc1ccc(cc1)C(=O)NCc1ccccc1C(F)(F)F)C(O)=O Show InChI InChI=1S/C19H18F3NO3/c1-12(18(25)26)10-13-6-8-14(9-7-13)17(24)23-11-15-4-2-3-5-16(15)19(20,21)22/h2-9,12H,10-11H2,1H3,(H,23,24)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Inhibition of human recombinant sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...				J Med Chem 59: 61-81 (2016) Article DOI: 10.1021/acs.jmedchem.5b01239 BindingDB Entry DOI: 10.7270/Q2348N8D
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50144799 (CHEMBL3764795) Show SMILES CC(Cc1ccc(cc1)C(=O)NCc1ccccc1C(F)(F)F)C(O)=O Show InChI InChI=1S/C19H18F3NO3/c1-12(18(25)26)10-13-6-8-14(9-7-13)17(24)23-11-15-4-2-3-5-16(15)19(20,21)22/h2-9,12H,10-11H2,1H3,(H,23,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Transactivation of human PPARgamma expressed in African green monkey COS7 cells incubated overnight by dual-glo luciferase reporter gene assay				J Med Chem 59: 61-81 (2016) Article DOI: 10.1021/acs.jmedchem.5b01239 BindingDB Entry DOI: 10.7270/Q2348N8D
					More data for this Ligand-Target Pair