BDBM50144841 (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine::(S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine::CHEMBL76781::Ro-60-0175::Ro-600175

SMILES: C[C@H](N)Cn1ccc2cc(F)c(Cl)cc12

InChI Key: InChIKey=XJJZQXUGLLXTHO-UHFFFAOYSA-N

Data: 10 KI  13 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50144841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50144841 ((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair