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BDBM50144931 CHEMBL3764432

SMILES: CCc1cccc(CC)c1NC(=O)N[C@@H](CC(C)C)C(=O)NO

InChI Key: InChIKey=ISOSJSYJSANOPI-AWEZNQCLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144931   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50144931
PNG
(CHEMBL3764432)
Show SMILES CCc1cccc(CC)c1NC(=O)N[C@@H](CC(C)C)C(=O)NO
Show InChI InChI=1S/C17H27N3O3/c1-5-12-8-7-9-13(6-2)15(12)19-17(22)18-14(10-11(3)4)16(21)20-23/h7-9,11,14,23H,5-6,10H2,1-4H3,(H,20,21)(H2,18,19,22)/t14-/m0/s1
PDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...


Eur J Med Chem 108: 21-7 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.021
BindingDB Entry DOI: 10.7270/Q2ZC84RN
More data for this
Ligand-Target Pair
HDACs


(Homo sapiens (human))
BDBM50144931
PNG
(CHEMBL3764432)
Show SMILES CCc1cccc(CC)c1NC(=O)N[C@@H](CC(C)C)C(=O)NO
Show InChI InChI=1S/C17H27N3O3/c1-5-12-8-7-9-13(6-2)15(12)19-17(22)18-14(10-11(3)4)16(21)20-23/h7-9,11,14,23H,5-6,10H2,1-4H3,(H,20,21)(H2,18,19,22)/t14-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...


Eur J Med Chem 108: 21-7 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.021
BindingDB Entry DOI: 10.7270/Q2ZC84RN
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50144931
PNG
(CHEMBL3764432)
Show SMILES CCc1cccc(CC)c1NC(=O)N[C@@H](CC(C)C)C(=O)NO
Show InChI InChI=1S/C17H27N3O3/c1-5-12-8-7-9-13(6-2)15(12)19-17(22)18-14(10-11(3)4)16(21)20-23/h7-9,11,14,23H,5-6,10H2,1-4H3,(H,20,21)(H2,18,19,22)/t14-/m0/s1
PDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of APN in human ES2 cells preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 1 hr by photometry


Eur J Med Chem 108: 21-7 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.021
BindingDB Entry DOI: 10.7270/Q2ZC84RN
More data for this
Ligand-Target Pair