BDBM50144946 CHEMBL3763918

SMILES Cc1cccc(c1C)CNC(=O)N[C@@H](CC(C)C)C(=O)NO

InChI Key InChIKey=OHCMBYBSFAJCOD-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144946   

TargetAminopeptidase N(Pig)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144946(CHEMBL3763918)
Affinity DataIC50: 70nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50144946(CHEMBL3763918)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed