BDBM50144963 CHEMBL3763358

SMILES COCCOc1cc2c(ncnc2cc1OC)-n1nc(nc1N)-c1ccccn1

InChI Key InChIKey=ZXNSGRMQSJUSGX-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144963   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataKd:  41nMAssay Description:Binding affinity to human TYK2 JH2 domain pseudokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144963(CHEMBL3763358)
Affinity DataKd:  130nMAssay Description:Binding affinity to human NEK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed