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BDBM50145004 CHEMBL3763903

SMILES: COc1cc2ncnc(-n3nc(nc3N)-c3cccnc3)c2cc1OC

InChI Key: InChIKey=BSSZKJAJHXRISB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine-protein kinase ATM


(Homo sapiens (Human))
BDBM50145004
PNG
(CHEMBL3763903)
Show SMILES COc1cc2ncnc(-n3nc(nc3N)-c3cccnc3)c2cc1OC
Show InChI InChI=1S/C17H15N7O2/c1-25-13-6-11-12(7-14(13)26-2)20-9-21-16(11)24-17(18)22-15(23-24)10-4-3-5-19-8-10/h3-9H,1-2H3,(H2,18,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Duke University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assay


J Med Chem 59: 559-77 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01092
BindingDB Entry DOI: 10.7270/Q2TM7D0W
More data for this
Ligand-Target Pair