BDBM50145135 CHEMBL3764188

SMILES Cn1nccc1C1C(Nc2cc(F)cc3c2c1n[nH]c3=O)c1ccc(F)cc1

InChI Key InChIKey=BVGJIMWIYVYPEI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145135   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145135(CHEMBL3764188)
Affinity DataEC50:  9.30nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145135(CHEMBL3764188)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed