BDBM50145152 CHEMBL3763446

SMILES Cn1ncnc1[C@@H]1[C@H](Nc2cccc3c2c1n[nH]c3=O)c1ccc(F)cc1

InChI Key InChIKey=VGCYLQAHCSEGLE-HZPDHXFCSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145152   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145152(CHEMBL3763446)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145152(CHEMBL3763446)
Affinity DataEC50:  5.10nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed