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BDBM50145172 CHEMBL3765175

SMILES: COc1ccc2nnnc(Nc3cccc(OC(F)(F)F)c3)c2n1

InChI Key: InChIKey=FDVZUYKVKVYNON-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145172   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM50145172
PNG
(CHEMBL3765175)
Show SMILES COc1ccc2nnnc(Nc3cccc(OC(F)(F)F)c3)c2n1
Show InChI InChI=1S/C14H10F3N5O2/c1-23-11-6-5-10-12(19-11)13(21-22-20-10)18-8-3-2-4-9(7-8)24-14(15,16)17/h2-7H,1H3,(H,18,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.02E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1224-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.032
BindingDB Entry DOI: 10.7270/Q25X2BT4
More data for this
Ligand-Target Pair