BDBM50145236 1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-pentan-1-one::CHEMBL82374

SMILES CCCCC(=O)N1CCC(CNc2nc-3c(CCOc4ccc(F)cc-34)s2)CC1

InChI Key InChIKey=KOGZUICFSKKHFC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50145236   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50:  7nMAssay Description:In vitro binding affinity of the compound against human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50:  100nMAssay Description:In vitro binding affinity of the compound against human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50:  6nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed