BindingDB logo
myBDB logout

BDBM50145592 CHEMBL3764752

SMILES: Cl.O=C(NCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1

InChI Key: InChIKey=QVZPIFYZIPUAKJ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145592   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50145592
PNG
(CHEMBL3764752)
Show SMILES Cl.O=C(NCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1
Show InChI InChI=1S/C22H24N4O.ClH/c27-22(19-8-10-23-11-9-19)24-12-13-25-14-16-26(17-15-25)21-7-3-5-18-4-1-2-6-20(18)21;/h1-11H,12-17H2,(H,24,27);1H
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.20n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex incubated for 30 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50145592
PNG
(CHEMBL3764752)
Show SMILES Cl.O=C(NCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1
Show InChI InChI=1S/C22H24N4O.ClH/c27-22(19-8-10-23-11-9-19)24-12-13-25-14-16-26(17-15-25)21-7-3-5-18-4-1-2-6-20(18)21;/h1-11H,12-17H2,(H,24,27);1H
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
42n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysis


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (Rat))
BDBM50145592
PNG
(CHEMBL3764752)
Show SMILES Cl.O=C(NCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1
Show InChI InChI=1S/C22H24N4O.ClH/c27-22(19-8-10-23-11-9-19)24-12-13-25-14-16-26(17-15-25)21-7-3-5-18-4-1-2-6-20(18)21;/h1-11H,12-17H2,(H,24,27);1H
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
385n/an/an/an/an/an/an/an/a



Dipartimento di Farmacia Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...


Eur J Med Chem 110: 133-50 (2016)


Article DOI: 10.1016/j.ejmech.2016.01.021
BindingDB Entry DOI: 10.7270/Q24X59N9
More data for this
Ligand-Target Pair