BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50145648 LP-778902::LX1032::LX1606::Telotristat::Xermelo::telotristat etiprate

SMILES: Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)-c1ccc(C[C@H](N)C(O)=O)cc1)C(F)(F)F

InChI Key: InChIKey=NCLGDOBQAWBXRA-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50145648
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Human)	BDBM50145648 (Xermelo \| LX1032 \| LX1606 \| LP-778902 \| Telotrista...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair