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BDBM50145871 CHEMBL3764668

SMILES: CS(=O)(=O)c1ccc(cc1Cl)C(CC1CCCC1)c1cc2cc(Br)cnc2[nH]1

InChI Key: InChIKey=LMEULCGFTKAMLF-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145871   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase/Glucokinase regulatory protein


(Homo sapiens (Human))
BDBM50145871
PNG
(CHEMBL3764668)
Show SMILES CS(=O)(=O)c1ccc(cc1Cl)C(CC1CCCC1)c1cc2cc(Br)cnc2[nH]1
Show InChI InChI=1/C21H22BrClN2O2S/c1-28(26,27)20-7-6-14(10-18(20)23)17(8-13-4-2-3-5-13)19-11-15-9-16(22)12-24-21(15)25-19/h6-7,9-13,17H,2-5,8H2,1H3,(H,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 115n/an/an/an/a



Servier Research Institute of Medicinal Chemistry

Curated by ChEMBL


Assay Description
Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...


J Med Chem 59: 687-706 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01594
BindingDB Entry DOI: 10.7270/Q2CF9S0F
More data for this
Ligand-Target Pair