BDBM50145918 CHEMBL3763993

SMILES CN1CCCN(Cc2ccc(CN)cc2)CC1

InChI Key InChIKey=AQLZGQUKWNQYPH-UHFFFAOYSA-N

Data  2 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145918   

TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataKd:  1.32E+5nMAssay Description:Binding affinity to human N-terminal truncated ChoKalpha1 (75 to 457 residues) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCholine kinase alpha(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of human N-terminal truncated ChoKalpha1 (75 to 457 residues) using choline chloride as substrate measured over 10 to 30 mins by coupled A...More data for this Ligand-Target Pair
TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataKd:  4.18E+5nMAssay Description:Binding affinity to immobilized recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50145918(CHEMBL3763993)
Affinity DataKd:  4.90E+5nMAssay Description:Binding affinity to carbonic anhydrase2 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed