BDBM50146167 Capmatinib::INC-280::INCB-28060::NVP-INC280::US10738052, Example 7::US11261191, Example 7::US20240294535, Compound Capmatinib::US9944645, 7

SMILES: CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

InChI Key: InChIKey=LIOLIMKSCNQPLV-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50146167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50146167 (Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair