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BDBM50146294 Biphenyl-2-carboxylic acid [3-methyl-4-(3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide::CHEMBL423868

SMILES: Cc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CC2CSCCN2Cc2ccccc12

InChI Key: InChIKey=NFTIDUCUMVSAOA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146294   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50146294
PNG
(Biphenyl-2-carboxylic acid [3-methyl-4-(3,4,11,11a...)
Show SMILES Cc1cc(NC(=O)c2ccccc2-c2ccccc2)ccc1C(=O)N1CC2CSCCN2Cc2ccccc12
Show InChI InChI=1S/C33H31N3O2S/c1-23-19-26(34-32(37)30-13-7-6-12-29(30)24-9-3-2-4-10-24)15-16-28(23)33(38)36-21-27-22-39-18-17-35(27)20-25-11-5-8-14-31(25)36/h2-16,19,27H,17-18,20-22H2,1H3,(H,34,37)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]AVP binding to recombinant human vasopressin V2 receptor


Bioorg Med Chem Lett 14: 2747-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.083
BindingDB Entry DOI: 10.7270/Q2QN679W
More data for this
Ligand-Target Pair