BindingDB logo
myBDB logout

BDBM50146307 Biphenyl-2-carboxylic acid [4-(9-chloro-3,4,11,11a-tetrahydro-1H,5H-2-thia-4a,10-diaza-dibenzo[a,d]cycloheptene-10-carbonyl)-phenyl]-amide::CHEMBL93195

SMILES: Clc1cccc2CN3CCSCC3CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c12

InChI Key: InChIKey=SWFWMZCZWMQLGN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50146307
PNG
(Biphenyl-2-carboxylic acid [4-(9-chloro-3,4,11,11a...)
Show SMILES Clc1cccc2CN3CCSCC3CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c12
Show InChI InChI=1S/C32H28ClN3O2S/c33-29-12-6-9-24-19-35-17-18-39-21-26(35)20-36(30(24)29)32(38)23-13-15-25(16-14-23)34-31(37)28-11-5-4-10-27(28)22-7-2-1-3-8-22/h1-16,26H,17-21H2,(H,34,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]AVP binding to recombinant human vasopressin V2 receptor


Bioorg Med Chem Lett 14: 2747-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.083
BindingDB Entry DOI: 10.7270/Q2QN679W
More data for this
Ligand-Target Pair