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BDBM50147150 2,2,2-Trifluoro-ethanesulfonic acid (3-cyclobutoxy-phenyl)-pyridin-3-ylmethyl-amide::CHEMBL105151

SMILES: FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC2CCC2)c1

InChI Key: InChIKey=PLFOOFNVJVQCNI-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147150   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50147150
PNG
(2,2,2-Trifluoro-ethanesulfonic acid (3-cyclobutoxy...)
Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC2CCC2)c1
Show InChI InChI=1S/C18H19F3N2O3S/c19-18(20,21)13-27(24,25)23(12-14-4-3-9-22-11-14)15-5-1-8-17(10-15)26-16-6-2-7-16/h1,3-5,8-11,16H,2,6-7,12-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 36n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Effective concentration against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 14: 3099-102 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69
More data for this
Ligand-Target Pair