BDBM50147399 2'-(2-Hydroxy-phenyl)-[2,4']bibenzooxazolyl-4-carboxylic acid methyl ester::CHEMBL111574::methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)benzo[d]oxazole-4-carboxylate

SMILES COC(=O)c1cccc2oc(nc12)-c1cccc2oc(nc12)-c1ccccc1O

InChI Key InChIKey=NGKIDJMAXLRJRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147399   

TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147399(methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)b...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity of compound against human DNA topoisomerase II, alpha was evaluated by ability to interfere with the relaxation of supercoiled pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50147399(methyl 2-(2-(2-hydroxyphenyl)benzo[d]oxazol-4-yl)b...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed