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BDBM50147427 1-Guanidino-isoquinoline-7-carboxylic acid::CHEMBL113114

SMILES: [#7]\[#6](-[#7])=[#7]/c1nccc2ccc(cc12)-[#6](-[#8])=O

InChI Key: InChIKey=SNRRLXIXUPWAFO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147427   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50147427
PNG
(1-Guanidino-isoquinoline-7-carboxylic acid | CHEMB...)
Show SMILES NC(N)=Nc1nccc2ccc(cc12)C(O)=O
Show InChI InChI=1S/C11H10N4O2/c12-11(13)15-9-8-5-7(10(16)17)2-1-6(8)3-4-14-9/h1-5H,(H,16,17)(H4,12,13,14,15)
PDB
MMDB

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Similars

Article
PubMed
1.00E+3n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against human urokinase-type plasminogen activator was evaluated using S-2444 as substrate


Bioorg Med Chem Lett 14: 3227-30 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.094
BindingDB Entry DOI: 10.7270/Q2125S3C
More data for this
Ligand-Target Pair