BDBM50148210 4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetrahydro-thiopyran-4-carboxylic acid hydroxyamide::CHEMBL112470

SMILES ONC(=O)C1(CCSCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=JSYMSOFUKLCCMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148210   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148210(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148210(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed