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BDBM50148307 ((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-2-methyl-propyl ester::CHEMBL118016

SMILES: CCCC[C@H](NC(=O)OC(C(C)C)C(C)C)C=O

InChI Key: InChIKey=IMEIARLUCDAOEN-LBPRGKRZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50148307
PNG
(((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-2-...)
Show SMILES CCCC[C@H](NC(=O)OC(C(C)C)C(C)C)C=O
Show InChI InChI=1S/C14H27NO3/c1-6-7-8-12(9-16)15-14(17)18-13(10(2)3)11(4)5/h9-13H,6-8H2,1-5H3,(H,15,17)/t12-/m0/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a 0.560n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrate


Bioorg Med Chem Lett 14: 3425-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.084
BindingDB Entry DOI: 10.7270/Q2SF2VMD
More data for this
Ligand-Target Pair