BindingDB logo
myBDB logout

BDBM50148440 2-{4-[2-(5,6,7,8-Tetrahydro-naphthalen-2-yloxy)-ethoxy]-benzyl}-malonic acid::CHEMBL115463

SMILES: OC(=O)C(Cc1ccc(OCCOc2ccc3CCCCc3c2)cc1)C(O)=O

InChI Key: InChIKey=IERLBDBFWXMBTP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148440   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50148440
PNG
(2-{4-[2-(5,6,7,8-Tetrahydro-naphthalen-2-yloxy)-et...)
Show SMILES OC(=O)C(Cc1ccc(OCCOc2ccc3CCCCc3c2)cc1)C(O)=O
Show InChI InChI=1S/C22H24O6/c23-21(24)20(22(25)26)13-15-5-8-18(9-6-15)27-11-12-28-19-10-7-16-3-1-2-4-17(16)14-19/h5-10,14,20H,1-4,11-13H2,(H,23,24)(H,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.11E+3n/an/an/an/a



Research Institute of Tsinghua University

Curated by ChEMBL


Assay Description
In vitro transcription activation on human peroxisome proliferator activated receptor-gamma (PPAR gamma)


Bioorg Med Chem Lett 14: 3507-11 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.053
BindingDB Entry DOI: 10.7270/Q2RF5TG1
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50148440
PNG
(2-{4-[2-(5,6,7,8-Tetrahydro-naphthalen-2-yloxy)-et...)
Show SMILES OC(=O)C(Cc1ccc(OCCOc2ccc3CCCCc3c2)cc1)C(O)=O
Show InChI InChI=1S/C22H24O6/c23-21(24)20(22(25)26)13-15-5-8-18(9-6-15)27-11-12-28-19-10-7-16-3-1-2-4-17(16)14-19/h5-10,14,20H,1-4,11-13H2,(H,23,24)(H,25,26)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 4.68E+3n/an/an/an/a



Research Institute of Tsinghua University

Curated by ChEMBL


Assay Description
In vitro transcription activation on human peroxisome proliferator activated receptor-delta (PPAR delta)


Bioorg Med Chem Lett 14: 3507-11 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.053
BindingDB Entry DOI: 10.7270/Q2RF5TG1
More data for this
Ligand-Target Pair