BDBM50148918 CHEMBL3769552
SMILES CNc1ncc2cc(-c3ccc(cc3Cl)-c3cccc(C)n3)c(=O)n(C[C@@H]3CCNCC3(F)F)c2n1
InChI Key InChIKey=ZVGQZSQDTLALCO-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50148918
Affinity DataKi: 7.90nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair