BDBM50148921 CHEMBL3770443

SMILES: CNc1ncc2cc(-c3ccc(cc3Cl)-c3cccc(C)n3)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1

InChI Key: InChIKey=ZBCMHWUFWQFPLV-UHFFFAOYSA-N

Data: 3 KI  14 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50148921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SIK2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 25 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase SIK2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 5 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 26 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 24 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 1 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 24 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase SIK2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	309	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 26 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 24 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 4 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase SIK1 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase SIK2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase SIK3 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase SIK2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 1 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 1 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 2 (Human)	BDBM50148921 (CHEMBL3770443) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair