BindingDB logo
myBDB logout

BDBM50149142 (1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[b]thiophen-2-yl-methanone::CHEMBL122440

SMILES: O=C(C1CN2CCC1CC2)c1cc2ccccc2s1

InChI Key: InChIKey=SHRLWGYNTYFYTI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149142   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50149142
PNG
((1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[b]thiophen-2-...)
Show SMILES O=C(C1CN2CCC1CC2)c1cc2ccccc2s1
Show InChI InChI=1S/C16H17NOS/c18-16(13-10-17-7-5-11(13)6-8-17)15-9-12-3-1-2-4-14(12)19-15/h1-4,9,11,13H,5-8,10H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.950n/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cells


Bioorg Med Chem Lett 14: 3781-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.091
BindingDB Entry DOI: 10.7270/Q2X066G1
More data for this
Ligand-Target Pair