BDBM50149208 2-Amino-quinolin-8-ol::CHEMBL119647

SMILES c1cc2ccc(nc2c(c1)O)N

InChI Key InChIKey=UFVLIVCXTIGACT-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149208   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit binding of [125I]MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataKi:  5.60E+4nMAssay Description:Binding affinity towards Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataKi:  1.38E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed