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BDBM50149547 4-[(4-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalene-1-carboxylic acid (3-fluoro-phenyl)-amide::CHEMBL182765

SMILES: Oc1ccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)cc1

InChI Key: InChIKey=YZHFFFVVOANGLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homeobox protein Brn-1


(Homo sapiens)
BDBM50149547
PNG
(4-[(4-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...)
Show SMILES Oc1ccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)cc1
Show InChI InChI=1S/C25H19FN2O4/c26-16-4-3-5-18(14-16)28-25(31)22-12-13-23(21-7-2-1-6-20(21)22)32-15-24(30)27-17-8-10-19(29)11-9-17/h1-14,29H,15H2,(H,27,30)(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.24E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay


Bioorg Med Chem Lett 14: 3875-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.068
BindingDB Entry DOI: 10.7270/Q2ZS2VZW
More data for this
Ligand-Target Pair
Homeobox protein Brn-2


(Homo sapiens)
BDBM50149547
PNG
(4-[(4-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...)
Show SMILES Oc1ccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)cc1
Show InChI InChI=1S/C25H19FN2O4/c26-16-4-3-5-18(14-16)28-25(31)22-12-13-23(21-7-2-1-6-20(21)22)32-15-24(30)27-17-8-10-19(29)11-9-17/h1-14,29H,15H2,(H,27,30)(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.38E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN2/DNA interaction by electrophoretic mobility shift assay


Bioorg Med Chem Lett 14: 3875-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.068
BindingDB Entry DOI: 10.7270/Q2ZS2VZW
More data for this
Ligand-Target Pair