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BDBM50149763 CHEMBL182172::{4-Oxo-5-[1-[4-((S)-2-phenyl-propoxy)-3-((S)-2,2,2-trifluoro-1-phenyl-ethoxy)-phenyl]-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-acetic acid

SMILES: C[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@@H](c1ccccc1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=LHYRKNFTTKMDNQ-WQFLCVAXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149763   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dolichyl-phosphate-mannose--protein mannosyltransferase 1


(Candida albicans)
BDBM50149763
PNG
(CHEMBL182172 | {4-Oxo-5-[1-[4-((S)-2-phenyl-propox...)
Show SMILES C[C@H](COc1ccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)cc1O[C@@H](c1ccccc1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C29H24F3NO5S2/c1-18(20-8-4-2-5-9-20)17-37-22-13-12-19(15-24-27(36)33(16-25(34)35)28(39)40-24)14-23(22)38-26(29(30,31)32)21-10-6-3-7-11-21/h2-15,18,26H,16-17H2,1H3,(H,34,35)/b24-15-/t18-,26+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Celltech R&D Ltd

Curated by ChEMBL


Assay Description
In vitro inhibition of Candida albicans protein mannosyl transferase 1


Bioorg Med Chem Lett 14: 3975-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.050
BindingDB Entry DOI: 10.7270/Q22J6B96
More data for this
Ligand-Target Pair