BDBM50149825 2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-1'',2'',3'',4'',5'',6''-hexahydro-[4,4'']bipyridinyl-3-carbonitrile::CHEMBL368427

SMILES: Nc1nc(cc(C2CCNCC2)c1C#N)-c1c(O)cccc1OCC1CC1

InChI Key: InChIKey=DYVFBWXIOCLHPP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50149825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50149825 (2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50149825 (2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50149825 (2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM50149825 (2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair