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BDBM50149854 CHEMBL180202::{4-[2-(4-Methoxy-phenylsulfanyl)-phenyl]-3-methyl-piperazin-1-yl}-acetic acid

SMILES: COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2C)cc1

InChI Key: InChIKey=PGAKBYJCYULAFF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149854   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149854
PNG
(CHEMBL180202 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2C)cc1
Show InChI InChI=1S/C20H24N2O3S/c1-15-13-21(14-20(23)24)11-12-22(15)18-5-3-4-6-19(18)26-17-9-7-16(25-2)8-10-17/h3-10,15H,11-14H2,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair