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BDBM50150370 CHEMBL183364::[Carboxymethyl-(6-methoxy-5-trifluoromethyl-naphthalene-1-carbonyl)-amino]-acetic acid

SMILES: COc1ccc2c(cccc2c1C(F)(F)F)C(=O)N(CC(O)=O)CC(O)=O

InChI Key: InChIKey=XSRPNVSTSJFCLR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150370   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50150370
PNG
(CHEMBL183364 | [Carboxymethyl-(6-methoxy-5-trifluo...)
Show SMILES COc1ccc2c(cccc2c1C(F)(F)F)C(=O)N(CC(O)=O)CC(O)=O
Show InChI InChI=1S/C17H14F3NO6/c1-27-12-6-5-9-10(15(12)17(18,19)20)3-2-4-11(9)16(26)21(7-13(22)23)8-14(24)25/h2-6H,7-8H2,1H3,(H,22,23)(H,24,25)
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UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibitory concentration against HCV NS5B RNA dependent RNA polymerase


Bioorg Med Chem Lett 14: 4221-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.013
BindingDB Entry DOI: 10.7270/Q2MC8ZFF
More data for this
Ligand-Target Pair