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BDBM50150860 CHEMBL361656::[(S)-5-Amino-1-(5-cyano-4,5-dihydro-pyrazole-1-carbonyl)-pentyl]-carbamic acid benzyl ester

SMILES: NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N1N=CCC1C#N

InChI Key: InChIKey=FARSJHLMCKSQJK-LYKKTTPLSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150860   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase IV


(Rattus norvegicus (rat))
BDBM50150860
PNG
(CHEMBL361656 | [(S)-5-Amino-1-(5-cyano-4,5-dihydro...)
Show SMILES NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N1N=CCC1C#N
Show InChI InChI=1S/C18H23N5O3/c19-10-5-4-8-16(17(24)23-15(12-20)9-11-21-23)22-18(25)26-13-14-6-2-1-3-7-14/h1-3,6-7,11,15-16H,4-5,8-10,13,19H2,(H,22,25)/t15?,16-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibitory concentration against rat dipeptidyl peptidase IV


Bioorg Med Chem Lett 14: 4461-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.046
BindingDB Entry DOI: 10.7270/Q2J9674N
More data for this
Ligand-Target Pair