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BDBM50150913 5-Methyl-thiazolidin-(2E)-ylideneamine::CHEMBL185505

SMILES: CC1CN=C(N)S1

InChI Key: InChIKey=IKFLLHVVKJTHAH-UHFFFAOYNA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50150913
PNG
(5-Methyl-thiazolidin-(2E)-ylideneamine | CHEMBL185...)
Show SMILES CC1CN=C(N)S1
Show InChI InChI=1/C4H8N2S/c1-3-2-6-4(5)7-3/h3H,2H2,1H3,(H2,5,6)
PDB
MMDB

NCI pathway
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Merck Research Laboratory

Curated by ChEMBL


Assay Description
Inhibitory activity against Inducible nitric oxide synthase


Bioorg Med Chem Lett 14: 4539-44 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.033
BindingDB Entry DOI: 10.7270/Q218377V
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50150913
PNG
(5-Methyl-thiazolidin-(2E)-ylideneamine | CHEMBL185...)
Show SMILES CC1CN=C(N)S1
Show InChI InChI=1/C4H8N2S/c1-3-2-6-4(5)7-3/h3H,2H2,1H3,(H2,5,6)
PDB

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Merck Research Laboratory

Curated by ChEMBL


Assay Description
Inhibitory activity against Endothelial nitric oxide synthase


Bioorg Med Chem Lett 14: 4539-44 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.033
BindingDB Entry DOI: 10.7270/Q218377V
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50150913
PNG
(5-Methyl-thiazolidin-(2E)-ylideneamine | CHEMBL185...)
Show SMILES CC1CN=C(N)S1
Show InChI InChI=1/C4H8N2S/c1-3-2-6-4(5)7-3/h3H,2H2,1H3,(H2,5,6)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Merck Research Laboratory

Curated by ChEMBL


Assay Description
Inhibitory activity against Neuronal nitric oxide synthase


Bioorg Med Chem Lett 14: 4539-44 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.033
BindingDB Entry DOI: 10.7270/Q218377V
More data for this
Ligand-Target Pair