BDBM50151074 CHEMBL364368::N-[4-((2R,8S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-2-yl)-phenyl]-N-methyl-acetamide

SMILES CN(C(C)=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#C)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key InChIKey=ZDCMJDVSSLHLLQ-GCNJZUOMSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50151074   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of glucocorticoid receptor dependent alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  34nMAssay Description:Inhibition of human Estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  570nMAssay Description:Inhibition of human Estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi:  790nMAssay Description:Inhibition of human Thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50151074(CHEMBL364368 | N-[4-((2R,8S,13S,14S,17R)-17-Ethyny...)
Affinity DataKi: >2.25E+3nMAssay Description:Inhibition of human Thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed