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BDBM50151202 2-Furan-2-yl-5-[4-(2-methylsulfanyl-thiophen-3-ylmethyl)-piperazin-1-yl]-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine::CHEMBL364988

SMILES: CSc1sccc1CN1CCN(CC1)c1nc(N)n2nc(nc2n1)-c1ccco1

InChI Key: InChIKey=SQYCMFDPNZUWLY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151202   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50151202
PNG
(2-Furan-2-yl-5-[4-(2-methylsulfanyl-thiophen-3-ylm...)
Show SMILES CSc1sccc1CN1CCN(CC1)c1nc(N)n2nc(nc2n1)-c1ccco1
Show InChI InChI=1S/C18H20N8OS2/c1-28-15-12(4-10-29-15)11-24-5-7-25(8-6-24)17-21-16(19)26-18(22-17)20-14(23-26)13-3-2-9-27-13/h2-4,9-10H,5-8,11H2,1H3,(H2,19,20,21,22,23)
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Similars

Article
PubMed
35n/an/an/an/an/an/an/an/a



Biogen Idec Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptor


J Med Chem 47: 4291-9 (2004)


Article DOI: 10.1021/jm0498405
BindingDB Entry DOI: 10.7270/Q2805235
More data for this
Ligand-Target Pair