BDBM50151315 CHEMBL3769534

SMILES CCOc1ccccc1N1CCN(CC(O)CN2C(=O)NC(C)(C2=O)c2ccc(F)cc2)CC1

InChI Key InChIKey=BHTLDHJPBYJAPF-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151315   

Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50151315(CHEMBL3769534)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50151315(CHEMBL3769534)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of 5-CT-induced cAMP production preincubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50151315(CHEMBL3769534)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50151315(CHEMBL3769534)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]-Raclopride from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed