BDBM50151347 2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine::2-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-[1,5]naphthyridine::CHEMBL185238

SMILES: Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1

InChI Key: InChIKey=LBPKYPYHDKKRFS-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50151347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Mouse)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-5 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 11 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase LCK (Mouse)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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