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BDBM50151803 (R)-3-Amino-4-(2-fluoro-phenyl)-1-thiazolidin-3-yl-butan-1-one::CHEMBL187118

SMILES: N[C@@H](CC(=O)N1CCSC1)Cc1ccccc1F

InChI Key: InChIKey=VSASDHRLBLNCMR-LLVKDONJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151803   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50151803
PNG
((R)-3-Amino-4-(2-fluoro-phenyl)-1-thiazolidin-3-yl...)
Show SMILES N[C@@H](CC(=O)N1CCSC1)Cc1ccccc1F
Show InChI InChI=1S/C13H17FN2OS/c14-12-4-2-1-3-10(12)7-11(15)8-13(17)16-5-6-18-9-16/h1-4,11H,5-9,15H2/t11-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.97E+4n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory concentration against quiescent cell proline dipeptidase


Bioorg Med Chem Lett 14: 4759-62 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.099
BindingDB Entry DOI: 10.7270/Q2XK8F1Q
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50151803
PNG
((R)-3-Amino-4-(2-fluoro-phenyl)-1-thiazolidin-3-yl...)
Show SMILES N[C@@H](CC(=O)N1CCSC1)Cc1ccccc1F
Show InChI InChI=1S/C13H17FN2OS/c14-12-4-2-1-3-10(12)7-11(15)8-13(17)16-5-6-18-9-16/h1-4,11H,5-9,15H2/t11-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 931n/an/an/an/an/an/a



Merck & Co.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Dipeptidyl peptidase IV


Bioorg Med Chem Lett 14: 4759-62 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.099
BindingDB Entry DOI: 10.7270/Q2XK8F1Q
More data for this
Ligand-Target Pair