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BDBM50152184 CHEMBL189754::[3-(6-Dimethylamino-4-methyl-pyridin-3-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-(1,4-dimethyl-pentyl)-amine

SMILES: CC(C)CCC(C)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C

InChI Key: InChIKey=DHQSNGINXKFVRT-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50152184
PNG
(CHEMBL189754 | [3-(6-Dimethylamino-4-methyl-pyridi...)
Show SMILES CC(C)CCC(C)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C
Show InChI InChI=1/C23H34N6/c1-14(2)9-10-16(4)25-21-12-17(5)26-23-22(18(6)27-29(21)23)19-13-24-20(28(7)8)11-15(19)3/h11-14,16,25H,9-10H2,1-8H3
PDB
MMDB

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Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor


J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair